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      1. 胱天蛋白酶8(CASP8)單克隆抗體

        Monoclonal Antibody to Caspase 8 (CASP8)

        CAP4; FLICE; MACH; MCH5; Cysteinyl Aspartate Specific Proteinases 8; Apoptotic cysteine protease; FADD-homologous ICE/ced-3-like protease; MORT1-associated ced-3 homolog

        • 胱天蛋白酶8(CASP8)單克隆抗體 產品包裝(模擬)
        • 胱天蛋白酶8(CASP8)單克隆抗體 產品包裝(模擬)
        • MAA853Hu22.jpg Western Blot; Sample: Jurkat cell lysate Primary Ab: 1.5μg/ml Mouse Anti-Human CASP8 Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
        • Certificate 通過ISO 9001、ISO 13485質量體系認證

        特異性

        該抗體是針對CASP8的小鼠單克隆抗體。在免疫組織化學染色和免疫印跡實驗中能識別CASP8。

        用法

        Western blotting: 0.5-2μg/mL
        Immunohistochemistry: 5-20μg/mL
        Immunocytochemistry: 5-20μg/mL
        Optimal working dilutions must be determined by end user.

        儲存

        經常使用則4°C保存。-20°C保存不超過兩年。避免反復凍融。

        穩定性

        熱穩定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產生。保質期內,在適當的條件下存儲,損失率低于5%。

        贈品

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        編號 適用物種:Homo sapiens (Human,人) 應用(僅供研究使用,不用于臨床診斷!)
        RPA853Hu02 胱天蛋白酶8(CASP8)重組蛋白 Positive Control; Immunogen; SDS-PAGE; WB.
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        參考文獻

        雜志 參考文獻
        Molecular Neurobiology Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations [Pubmed:25502462]
        Journal of Ethnopharmacology Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells [Pubmed:29555410]
        Clinical?And Experimental Pharmacology And Physiology? Diallyl sulfide alleviates cisplatin‐induced nephrotoxicity in rats via suppressing NF‐κB downstream inflammatory proteins and p53/Puma signalling pathway [Pubmed:29266336]
        Environmental Toxicology Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine‐treated male albino mice [Pubmed: 31087429]
        Environ Toxicol Pharmacol. Targetingp53/TRAIL/caspase-8 signaling by adiponectin reverses thioacetamide-induced hepatocellular carcinoma in rats [Pubmed: 31421311]
        Journal of Biochemical and Molecular Toxicology Tranilast attenuates methotrexate‐induced renal and hepatic toxicities: Role of apoptosis‐induced tissue proliferation [Pubmed: 32045101]
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        Odontology Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells [Pubmed: 33206337]
        Int Immunopharmacol Cardio-protective impact of gabapentin against doxorubicin-induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling [Pubmed: 33199237]
        ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY Chemo-preventive effect of crocin against experimentally-induced hepatocarcinogenesis via regulation of apoptotic and Nrf2 signaling pathways [Pubmed: 32942000]
        Environ Sci Pollut Res Int Potentiation of the apoptotic signaling pathway in both the striatum and hippocampus and neurobehavioral impairment in rats exposed chronically to a low? dose of?… [Pubmed: 32915453]
        J Biochem Mol Toxicol Tranilast abrogates cisplatin?\induced testicular and epididymal injuries: An insight into its modulatory impact on apoptosis/proliferation [34047436]
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